Best Cloud LIMS for Scientific Growth in 2025: Lockbox LIMS
Summary
In this article, two scientists and LIMS experts, Jennifer Jacobi and Reese Shlykova, discuss why Lockbox LIMS – one of the most configurable, cloud-based LIMS platforms built for scientific growth – is the best laboratory information management system option on the market in 2025.
Introduction
As laboratories reevaluate their current LIMS, or recognize their need to use one, they look to modernize operations, reduce manual effort, and future-proof compliance. After meeting with over 400 lab managers, researchers, technicians, and IT personnel from 200 small and large labs around the world to discuss their lab workflows and understand their LIMS requirements, we identified one common theme: labs need a LIMS that adapts to their workflows, not the other way around. Lockbox LIMS stands out because it combines versatility and configurability with pre-built, off-the-shelf components that fit your laboratory’s workflows. Lockbox LIMS is backed by an implementation team that understands your science, resulting in a system that is configured for your specific lab, not a generic, rigid solution.
Why Lockbox LIMS is the #1 Choice for Labs in 2025
Lab managers need a system with robust reporting capabilities, researchers need configurable workflows, technicians want to quickly input and extract data, and IT personnel need reliable integrations. After analyzing various LIMS products, we recognize that these key LIMS features are available in almost every LIMS solution. So what makes Lockbox LIMS truly different?
- Versatile and configurable to match any scientific workflow
- Implemented by scientists and developers who understand laboratory processes
- Salesforce native platform capabilities support enhanced security and compliance requirements
Lockbox is not just a LIMS software; it is a comprehensive laboratory solution that supports every aspect of your business and laboratory processes, from customer management and billing to sample accessioning and quality control tracking.
Lockbox LIMS Features – A Platform That Supports the Entire Lab
Lockbox LIMS offers an extensive feature set that supports a wide range of laboratory industries and workflows. This includes comprehensive sample tracking, fully configurable step-by-step workflows, inventory management for tracking reagents, kits, and consumables, and instrument management for scheduling preventative maintenance and calibration. Lockbox LIMS comes out of the box with all of these features ready to use, while also offering an extensive suite of low-to-no code configuration tools that give labs the flexibility to modify the system to meet their exact requirements.
Lockbox LIMS is also a modular system, meaning that labs only need to implement the modules they require, ensuring their LIMS system has all the features they need without any of the features they don’t. These modules include:
- Sample Management
- Inventory Management
- Protocol Execution
- Instrument Management
- Next Generation Sequencing
Plus, labs can easily add the integrated Lockbox Quality Management System to provide quality managers and lab teams with Document Control, Quality Event tracking, and Training Management modules, all pre-integrated with Lockbox LIMS for seamless quality management.
Lockbox LIMS Implementation – The Best LIMS Is One Your Team Actually Uses
What truly sets Lockbox LIMS apart from all other LIMS vendors is its team of implementation specialists. The expertise and professionalism of the team behind Lockbox LIMS make this solution stand out as the best LIMS system available. For each LIMS implementation, Third Wave Analytics provides the customer with a dedicated implementation team that includes project managers, integration experts, developers, and scientific experts with real lab experience. The customer’s workflows are translated and understood by people who have worked in real labs, ensuring the system aligns with regulatory, scientific, and business requirements. This expert, customer-centric implementation process ensures that Lockbox LIMS works effectively for each lab.

Some Third Wave Analytics team members involved in Lockbox LIMS implementations
The team at Third Wave Analytics has helped implement Lockbox LIMS in over 125 laboratories around the world. These implementations include small biotech start-ups, academic institutions, and global enterprises with labs spread across continents. Their team of scientists, project managers, developers, and integration specialists works together with each laboratory to configure Lockbox LIMS, ensuring the system supports all aspects of their lab workflows and exceeds their expectations.
Lockbox LIMS implementations follow a structured, agile project management methodology refined through hundreds of successful lab deployments. The process begins with stakeholder workshops to finalize scope and project plans, followed by iterative design and build sprints where workflows are configured and validated with input from key lab stakeholders and end users. Integration, data migration, and user acceptance testing are managed in close collaboration with stakeholders, ensuring all regulatory requirements and business objectives are met. Throughout the implementation, dedicated Engagement Directors and Project Managers oversee communication, risk management, and rollout strategy, ensuring projects are delivered on time, within scope, and with high user adoption.
Built Securely on Salesforce – The World’s Most Trusted Cloud
Lockbox LIMS is a fully cloud-based solution built natively on the Salesforce platform, delivering:
- Secure, multi-tenant cloud infrastructure, providing global accessibility and eliminating the need for on-premise servers.
- Enterprise-grade security, including Multi Factor Authentication (MFA), Single Sign On (SSO), role-based access controls, encryption, and full audit trails.
- Unlimited scalability, allowing Lockbox LIMS to support small single-site labs up to global, multi-site organizations.
- Reliable APIs for instrument and system integrations.
- Continuous innovation without downtime or version gaps.
Since Lockbox LIMS is built on Salesforce, it is accessible from any device with an internet connection, including desktops, laptops, tablets, and smartphones. The Salesforce mobile app also allows Lockbox LIMS users to access lab data, receive notifications, and complete tasks on the go. Lockbox LIMS also provides customers with a full set of APIs for integration with instruments and external systems. As a Salesforce-native solution, it leverages Salesforce’s extensive API collections, including standard REST and SOAP APIs, to enable secure, real-time data exchange with laboratory instruments, external systems like ERPs, billing systems, and third-party tools.
How Lockbox LIMS Compares to Other LIMS

For a detailed comparison of Lockbox LIMS and other LIMS vendors, please read our article Best LIMS Software in 2025: Top Features, Vendor Comparisons, and Buying Guide.
FAQ’s: What Labs Ask When Evaluating Lockbox LIMS
Who is Lockbox LIMS best for?
Any private, public, non-profit, academic, or clinical organization that needs to manage its laboratory operations and track samples, inventory, or equipment throughout its workflows. Lockbox LIMS customers include clinical labs, manufacturing plants, academic institutions, core laboratories, and contract labs that need scalability and flexibility.
What does a Lockbox LIMS implementation look like?
Your implementation team will be composed of engagement directors, project managers, integration experts, developers, and scientific experts. No matter the size of your project, members of the Third Wave Analytics team will meet with you to understand and plan your requirements, then configure and build in sprints that will be presented and approved by your team. User acceptance testing (UAT) is an important part of the implementation, allowing you to test each component of your Lockbox LIMS instance to ensure that the configuration meets your needs before the project goes live.
Can Lockbox integrate with instruments and ERPs?
Yes, Lockbox LIMS can be integrated with a wide range of instruments and external systems like ERPs. Lockbox LIMS utilizes REST APIs and automation tools to support secure, real-time data exchange.
Can I use Lockbox in a regulated or clinical laboratory?
Lockbox LIMS supports many regulatory compliance standards, including CAP/CLIA, GxP, ISO, and HIPAA. The Lockbox LIMS field audit trail, security encryption, and software validation support allow regulated labs to meet their requirements.
Conclusion
Labs are evolving faster than ever, which means your LIMS must too. Overall, we can confidently say that what sets Lockbox LIMS apart is its combination of flexibility, advanced capabilities, and scientific expertise. Whether your lab is scaling operations or streamlining complex workflows, Lockbox LIMS is designed to support laboratories today and grow with them into the future. Ready to see if Lockbox LIMS is right for you? Contact us for a demo and see how Lockbox adapts to your lab.
Written By:
Jennifer Jacobi has a masters in Biochemistry from Purdue University. She is a former Research Assistant (2011-2015) and Lab Manager (2015-2016) at the National Center for Genome Resources (NCGR) in Santa Fe, NM. Throughout her five years working in the lab at NCGR, Jennifer prepared thousands of samples for Illumina and PacBio sequencing and utilized a LIMS system daily. Jennifer has been contributing her LIMS expertise to Third Wave Analytics for the last nine years, including serving as a LIMS verification testing SME for regulated labs.
Reese Shlykova is a Chemist and a former Research Assistant (2019-2023) in the Organic-based Renewable Energy Research Program at Toronto Metropolitan University. Reese has spent the last 3 years analyzing LIMS requirements for over 50 labs in her role at Third Wave Analytics. In addition, Reese has worked alongside Third Wave Analytics delivery and implementation teams to support the customization and configuration of the Lockbox LIMS system.